MICROWAVE ASSISTED SYNTHESIS OF 2-PIPERIDONE AND 2-PYRROLIDONE- MORPHINANES

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  • TITLE: MICROWAVE ASSISTED SYNTHESIS OF 2-PIPERIDONE AND 2-PYRROLIDONE- MORPHINANES
  • AUTHOR(S): D. Vasilev
  • ABSTRACT: The conventional technique of heat is slower and leads to degradation once the products. The use of microwaves not only reduces the reaction time from hours to minutes, but increased the yield and selectivity. These are the reasons microwave organic synthes is can be applied in industry.The microwave heat is very efficient source of energy and can be used to greatly reduce the reaction time of a series of organic reactions. In this work is studied referral codeinone in reactions of hetero-cyclization with 1,3-binucleophiles, with the participation of the α, β-unsaturated ketone system in its molecule.
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